The best way to experience a city’s true spirit is through its neighbourhoods – wandering local streets, browsing indie shops and dining where the locals do. From buzzing downtowns to historic Latino quarters, LGBTQ+ hub, and vibrant Chinatowns, each area has its own unique energy. To help you find the most exciting spots, we’ve ranked America’s 35 coolest neighbourhoods for 2025 – the places with the best food, culture, and nightlife right now.

Read on to discover our ranking of America's coolest neighbourhoods...