Situated in the Sonoran Desert, CIVANA Wellness Resort and Spa is a recent arrival to the wellness break world. Designed by long-time Oprah Winfrey collaborator Deepak Chopra, this ayurveda-inspired retreat centres around four main pillars: movement, spa, nourishment and discovery. Expect vegan food, yoga, customised spa treatments, private consultations, daily health classes and a lot of meditation.